GHK-Cu (Copper Peptide) Research Vial 50mg

GHK-Cu (glycyl-L-histidyl-L-lysine-copper) is a naturally occurring tripeptide-copper(II) complex found in human plasma, saliva, and urine. First isolated in 1973 by Dr. Loren Pickart, this peptide-copper chelate has been the subject of 62 PubMed-verified studies investigating its role in tissue regeneration, collagen metabolism, and inflammatory modulation. **Mechanism of Action** GHK-Cu functions as a copper ion delivery system, transporting bioavailable Cu²⁺ to cells and tissues where it serves as an essential cofactor for multiple enzymatic processes. The copper ion is critical for lysyl oxidase activity—the enzyme responsible for collagen and elastin crosslinking—and for superoxide dismutase (SOD), a primary antioxidant defense enzyme. Beyond copper delivery, GHK-Cu exerts direct biological effects by attracting macrophages and mast cells to sites of tissue injury and modulating gene expression. Research has demonstrated that GHK-Cu upregulates genes associated with tissue health and repair while downregulating inflammatory mediators. It specifically stimulates synthesis of collagen types I, III, and V—the primary structural collagens of connective tissue. **Research Applications** Investigational applications of GHK-Cu span multiple research domains: - Wound healing and tissue repair kinetics - Collagen synthesis and dermal matrix remodeling - Copper-dependent enzyme activity (lysyl oxidase, SOD) - Inflammatory mediator modulation - Anti-aging and cellular regeneration pathways - Hair follicle growth cycle regulation The compound has been investigated in both injectable (1-3 mg SubQ) and topical (1-2 mg/mL) formulations, reflecting its versatility in research protocols. **Quality Documentation** Each batch undergoes HPLC purity analysis (≥98%), mass spectrometry identity confirmation, and copper content verification via inductively coupled plasma (ICP) analysis. Certificate of Analysis available upon request. Intended for laboratory research use only. Not for human or veterinary administration.